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This article will cover everything about the medicinal CBD oil for migraine cure, research, risk, and legality of using medicinal CBD oil for migraine treatments.

Migraine attacks can lead to a typical headache to any kind of allergy-related headache. It may continue from 4 to 72 hours.

Some normal activities, like noise or light, can make your symptoms more serious.

Whereas some pain killer medicines could be useful against migraine attacks, but their side effects might be bothersome.

By this time, you may consider taking cannabidiol (CBD).

Medicinal CBD Oil


CBD is made from a plant called cannabis.

And it is getting more popular as a natural treatment for specific medical conditions.

But, there has been limited research on medicinal CBD oil for migraine treatments.

Some previous researchers found that the mixed uses of CBD and tetrahydrocannabinol (THC) were helpful for the migraine treatments.

Currently, you will not find many studies about the particular effects of CBD for migraine treatments.

The main cause is for limited research on CBD and also due to the legalization of cannabis.

A small number of studies suggested that CBD oil could help treat some chronic pains, including migraines.

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Study on CBD and THC

In 2017, some studies showed that the benefits of cannabinoids in migraine treatment by the European Academy of Neurology (EAN).

In the first phase of their research, 48 patients of chronic migraines were given a combination of these two kinds of stuff.

At first, there was no effect when the dosages (THC-CBD mixture) were given under 100 mg (milligram).

It was then shown that acute pain was lessened by 55 percent due to increasing the dose to 200 mg.

In the second phase, those 79 people were given a daily dose of 200 mg of the THC-CBD mixture.

For three months, the treatment period lasted, and after a month, the treatment ended, a follow-up took place.

This decrease was only noticed in participants who had migraine attacks from a very young age.

The researchers showed that cannabinoids worked effectively against cluster headaches only if the participant started suffering from migraine attacks when they were a child.

Studies on Medical Marijuana

A study on medical Marijuana conducted by Pharmacotherapy was published in 2016.

Forty-eight people were tested in that study. Among them, 48% showed a drop in migraine attacks overall.

The most complained issue was sleepiness, while on the other hand, some faced difficulty finding the right dose.

Those who took Marijuana in the edible form, compared to those used as an inhaler or any other way, have suffered from most side effects.

The majority of the participants preferred to replace their prescribed medicines- normally opioids or opiates- with cannabis.

Study on Nabilone

In 2012 an Italian study looked at the effects of Nabilone, a synthetic version of THC, used to treat headache disorder.

The experiment conducted on 26, people suffering from medication overuse, .50mg of Nabilone a day or 400mg of ibuprofen, in oral doses (i.e., Tablets and pills)

The participants went without any medication for one week after having one drug for two months.

Then the participants shifted to the other medicine for the last two months.

Both of the medicines worked effectively.

But Nabilone showed better results such as greater improvement and better life quality.

Nabilone also showed less pain intensity and less reliability on drugs.

The frequency of migraine attacks wasn’t affected by any of the drugs, which the researchers said is due to the short period of the study.

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How CBD works?

The way CBD works is quite complicated. It interacts with CB1 and CB2, which are cannabinoid receptors (a protein) of our body.

Though this process isn’t fully understood, the receptors can have an impact on your immune system.

For instance, CBD can stop our bodies from absorbing. This substance called anandamide is connected with pain management.

By managing high levels of anandamide in your bloodstream, your feeling of pain will be less.

CBD also limits our body’s infection level, helping decrease our pain level and other immune system responses.

There isn’t enough research to fully understand how CBD has an impact on our bodies.

CBD Oil for Migraine


How to use CBD

In the USA, the lawmakers are having debates over the quality and worthiness of cannabis and also similar kinds of products.

However, Marijuana is being used for medical purposes for a long time.

The National Center for Complementary and Integrative Health (NCCIH) said that cannabis had been used as an alternative medicine for more than 3,000 years. Some of them have been used for the management of:

  • Pain
  • Symptoms related to the disorder of our nervous system
  • Infection

CBD oil can be:

  • Taken via vaping
  • Taken by swallowing it
  • By applying externally to a particular body part (topically)

The chances of having side effects are quite low if you take CBD orally. You can:

  • Use droplets of CBD by taking it via your tongue.
  • Take capsules of CBD.
  • Mix CBD with your meal or drink

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You may be benefited by taking CBD via vaping at home if you are suffering from migraines, and it isn’t necessary for you to go outside.

The National Cancer Institute (NCI) said that by taking CBD through inhalation is the fastest method of them all.

Presently, you won’t find any guidelines about the suitable dosage for migraine attacks.

You should consult with your doctor when it comes to finding the most suitable dose for you.

If you take CBD Oil for Migraine for the first time, it is recommended to start with the smallest dosage.

If your body starts to adjust with the oil, then you may consider taking the full recommended dose.

In this way, the risk of having side effects is quite low.

Potential Side Effects and Risks

Research says that the overall side effects of medicinal CBD oil for migraine treatments are quite small.

That is why people are choosing over-the-counter drugs and pain medicines for addiction.

Tiredness, sleepiness are some likely side effects, a change in your weight, and your food taste are also expected to be potential side effects.

In mice, the liver infection was also detected as they were forcefully given high doses of CBD.

How much you are likely to have side effects relies on how you use medicinal CBD oil for migraine treatments.

For example, vaping can cause problems in your lungs.

This can lead to:

  • Long term cough
  • Wheezing (a high-pitched whistling sound made while breathing)
  • Difficulties when breathing

If you have asthma or any other kind of lung disease, your doctor may not recommend taking CBD via vaping.

You should talk with your doctor if you are unsure about the potential side effects or how your body may manage those side effects.

Be careful if you’re taking other medicines or dietary supplements, as they can have interactions with CBD. The drugs CBD may have interactions with include:

  • Antibiotics
  • Antidepressants
  • Blood thinners (medicines that help blood flow smoothly)

Be more careful if you are taking drugs or supplements that react with grapefruits.

Grapefruit and CBD both tend to react with enzymes (substances that speed up chemical reactions in our body) like cytochromes P450 (CYPs) that help our bodies to digest drugs.

Will CBD get you high?

CBD oils don’t always feature THC, though they are formed from cannabis.

THC is the kind of cannabinoid that tends to make you feel high if taken through smoking cannabis.

Two kinds of CBD-strains are commonly found in the market:

  • Dominant
  • Rich

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The dominant-strain contains little to no THC, while the rich-strain features both cannabinoids. CBD that doesn’t contain THC doesn’t tend to affect your mind.

Even if you chose to use a combination product, CBD would prevent THC from affecting our body.

This is one of the reasons why CBD oil is a better option than medical Marijuana.

Is CBD Legal?

In the USA, medicinal CBD oil for migraine products that contain Marijuana are not legal at the federal level, but in some state-levels, they can be found legitimate.

CBD products that are Hemp-derived (contains less than 0.3 percent THC) are considered legal by the federal government, but according to some states, it’s deemed to be illegal.

If you are in the USA, then check your state’s law or any other state’s law you are planning to visit them.

Please note that the FDA doesn’t approve CBD products that are considered nonprescription, and their labeling can be inaccurate.


Because of some psychoactive (in a way that affects a person’s mind) portions of traditional Marijuana, cannabis is banned in some of the parts of the USA.

But here is good news, many states have started to vote in favor of the approval of cannabis for medical purposes only.

Other states have approved cannabis for medical purposes and also for purposes of self-satisfaction.

If you are a resident of a state where Marijuana is considered legal for medicinal purposes and purposes of self-satisfaction, you should also have access to CBD oil.

But if your state has approved Marijuana for medical purposes only, then you must have a marijuana card before buying CBD oil for migraine products. You can get a marijuana card through your doctor.

This license is essential if you want to use all forms of cannabis, including CBD.

All forms of cannabis are still considered illegal in some states. At the federal level, Marijuana is still regarded as harmful and against the law.

You should note your state’s laws or any other state’s laws you are planning to visit.

If cannabis is banned from that state or you need a license for using it, but unfortunately, you don’t have the permission, then you can be charged for the possession of cannabis.

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Talk to your doctor

More research is required before applying medicinal CBD oil for migraine treatments. But still, if you are interested, see your doctor.

He/she can help you find the right dose for you and can also help in going through the legal procedures.

If you consider taking CBD, then think of it as other medicines that you choose for migraines.

You may have to adjust until you find the right dose for you, and it may take some time to work.